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Prof. Dr. Simone Grandini

LECTURE TITLE: ENDODONTICS & BEYOND: DECODING MULTIMORBIDITY IN ROOT-TO-CROWN TREATMENT PLANNING

Recent evidence reveals that successful endodontic treatment involves more than just effective root canal therapy. Indeed, long-term success requires also careful consideration of coronal restoration. The choice of restoration depends heavily on the residual coronal tooth structure, which can range from intact Class I access cavities to severely compromised or decapitated teeth.

Adding complexity is the management of patients with multimorbidity, where systemic conditions such as diabetes, cardiovascular disease, and psoriasis can influence the healing process of periapical lesions and the durability of restorations. Indeed, recent research demonstrated that oral conditions such as periapical lesions, periodontitis, and caries are associated with elevated levels of chronic inflammatory mediators, which can influence systemic health. This highlights the potential connection between oral and systemic health, suggesting that oral health conditions may be risk factors for various systemic diseases and vice versa. Given this interplay, it is essential to evaluate patients holistically, considering both the specific needs of the tooth and the broader health context. This presentation will examine how these elements intersect, reviewing the latest evidence and trends in coronal restoration techniques and their application to varying levels of tooth structure loss. By integrating clinical evidence with a comprehensive approach to patient health, the session aims to offer practical strategies for optimizing endodontic outcomes and addressing both technical and systemic considerations effectively.

Prof. Simone Grandini is Full Professor of Endodontics and Restorative Dentistry at the University of Siena, where he also serves as Vice Director of the Department of Medical Biotechnologies, Dean of the School of Dentistry and Dental Prosthodontics, Head of the Department and Chair of Endodontics, Periodontology, Paediatric and Restorative Dentistry, and Dean of the School of Dental Hygienists.

He is currently President of SIDOC (Italian Society of Conservative Dentistry), an active member of IAED (Italian Academy of Esthetic Dentistry), AIE (Italian Academy of Endodontics), SIE (Italian Society of Endodontics), IADR, as well as Style Italiano and Style Italiano Endodontics. He is also the Founder of Style Italiano Research.

Prof. Grandini has been recognized internationally as Honorary Professor at the University of Hong Kong and awarded Doctor Honoris Causa by the Carol Davila University of Bucharest. He also holds a PhD from the University of Siena on “Basic and clinical aspects of selection and application of fiber posts.”

Over the past 20 years, he has authored more than 300 scientific papers in international journals and delivered over 1,000 lectures worldwide across Europe, the Americas, Asia, Africa, and Oceania, establishing himself as a global leader in Endodontics and Restorative Dentistry.



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